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You are here:Home » Antibodies » Abs to RNA Processing » Anti -CUGBP2 (CUGBP Elav-like Family Member 2, CELF-2, Bruno-like Protein 3, CUG Triplet Repeat RNA-binding Protein 2, CUG-BP2, CUG-BP- and ETR-3-like Factor 2, ELAV-type RNA-binding Protein 3, ETR-3, Neuroblastoma Apoptosis-related RNA-binding Protein, hNAPOR,

Anti -CUGBP2 (CUGBP Elav-like Family Member 2, CELF-2, Bruno-like Protein 3, CUG Triplet
Repeat RNA-binding Protein 2, CUG-BP2, CUG-BP- and ETR-3-like Factor 2, ELAV-type
RNA-binding Protein 3, ETR-3, Neuroblastoma Apoptosis-related RNA-binding Protein, hNAPOR,

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B
RNA editing is an important mechanism for regulating genetic plasticity through the generation of alternative protein products from a single structural gene. There are two types of substitutional RNA exist in mammals, namely A-to-I and C-to-U RNA editing. The best-characterized example of C-to-U RNA editing involves the nuclear transcript encoding intestinal apolipoprotein B (apo B)). Apo B RNA editing changes a CAA to a UAA stop codon, generating a truncated protein, apoB48. The functional complex includes a minimal core composed of apobec-1 and ACF, that function as an adaptor protein by binding both the deaminase and the RNA substrate. The RNA binding proteins also include CUGBP2 which along with Apobec-1 binds to the consensus binding sequence UUUN (A/U) U, present in c-myc, VEGF and Cyclooxygenase-2 (COX2).
Catalog #C7948-50F
ApplicationsSuitable for use in ELISA, Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 1-10ug/ml (ECL)
ELISA: 0.5-1ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile ddH2O or PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a lyophilized powder from PBS, 0.05% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to 18aa of human CUGBP2 (KLH).
SpecificityRecognizes human CUGBP2.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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