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You are here:Home » Antibodies » Abs to Cullin » Anti -Cullin 1, CT (CUL1, Cullin-1, CUL-1)

Anti -Cullin 1, CT (CUL1, Cullin-1, CUL-1)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Serum E B IP IH
Cullin-1 is a negative regulator of the cell cycle that controls the abundance of G1 cyclins during embryogenesis; Cul1 mutants produce abnormally small cells due to an accelerated progression of the cell cycle G1-to-S-phases and the absence of mitotic arrest phase. Null mutations cause hyperplasia of all tissues. Cul-1 is part of the SCF ubiquitin ligase complex with S KP1 and F box-containing protein. Cul-1 is homologous to the yeast cdc53 protein.
Catalog #C7949-06A
ApplicationsSuitable for use in Western Blot, ELISA, Immunoprecipitation and Immunohistochemistry. Other applications not tested.
Recommended DilutionELISA: 1:2000-1:10,000
Western Blot: 1:500-1:1000
Immunohistochemistry (Formalin fixed paraffin embedded): 1:500
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
CAS Numbern/a
Clone TypePolyclonal
HostRabbit
SourceHuman
ConcentrationNot determined
FormSupplied as a liquid, 0.1% sodium azide.
PuritySerum
ImmunogenSynthetic peptide corresponding to aa742-752 of human Cullin 1 at C-terminal (KLH).
SpecificityRecognizes human Cullin 1. Species sequence homology: Mouse.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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