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You are here:Home » Antibodies » Abs to Cullin » Anti -Cullin 3 (CUL-3)

Anti -Cullin 3 (CUL-3)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B IP
Cullin 3 is a member of the family of human Cullin genes (CUL-1, -2, -3, -4a, -4b and -5) homologous to the S. cerevisiae cdc53 gene.
Catalog #C7949-20D
Cullin 3 forms a tight complex with cyclin E and targets it for ubiquitination, which leads to its degradation by proteosomes.
ApplicationsSuitable for use in Western Blot and Immunoprecipitation. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
HostRabbit
SourceHuman
Concentration~0.2mg/ml
FormTris-buffered Saline 0.1% BSA
PurityPurified by immunoaffinity chromatography.
ImmunogenAntibody was affinity purified using an epitope specific to Cul3 immobilized on solid support.The epitope recognized by this antibody maps to a region between residue 650 and 700 of human cullin 3 using the numbering given in entry NP_003581.1 (GeneID 8452).A.
SpecificitySpecies Crossreactivity: Human and Mouse.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesCul3, Cul-3, Cullin3, Cullin 3


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