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Specifications

Clone Host Grade Applications Polyclonal Rabbit Affinity Purified B

Cullin 3 is a member of the family of human Cullin genes (CUL-1, -2, -3, -4a, -4b and -5) homologous to the S. cerevisiae cdc53 gene.
Catalog #	C7949-20E
	Cullin 3 forms a tight complex with cyclin E and targets it for ubiquitination, which leads to its degradation by proteosomes.
Applications	Suitable for use in Western Blot. Other applications not tested.
Recommended Dilution	Optimal dilutions to be determined by the researcher.
Storage and Stability	May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
CAS Number	n/a
Clone Type	Polyclonal
Host	Rabbit
Source	Human
Concentration	~1mg/ml
Form	Tris-citrate/phosphate buffer, pH 7 to 8
Purity	Purified by immunoaffinity chromatography.
Immunogen	Antibody was affinity purified using an epitope specific to Cul3 immobilized on solid support.The epitope recognized by this antibody maps to a region between residue 718 and 768 of human cullin 3 using the numbering given in entry NP_003581.1 (GeneID 8452).A.
Specificity	Species Crossreactivity: Human and Mouse.
Important Note	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate names	Cul3, Cul-3, Cullin3, Cullin 3