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Anti -Cullin 3, NT (CUL3, Cullin-3, CUL-3, KIAA0617)
Anti -Cullin 3, NT (CUL3, Cullin-3, CUL-3, KIAA0617)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Serum |
E B IP IH |
|
| Serves as a substrate-specific adapter for the CUL3-based ubiquitin-protein E3 ligase complex. Negatively regulates the Wnt signaling pathway via the targeted ubiquitination and subsequent proteolysis of DVL3. Component of an ubiquitin-protein E3 ligase complex which includes at least CUL3 and KLHL12. This complex interacts with DVL3 upon activation of the Wnt signaling pathway by WNT3A. | | | Catalog # | C7949-21C | | Applications | Suitable for use in Western Blot, Immunoprecipitation, ELISA and Immunohistochemistry. Other applications not tested. | | Recommended Dilution | ELISA: 1:2000-1:10,000 | | Western Blot: 1:500-1:1000 | | Immunohistochemistry (Formalin fixed paraffin embedded): 1:500 | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Host | Rabbit | | Source | Human | | Concentration | Not determined | | Form | Supplied as a liquid, 0.01% sodium azide. | | Purity | Serum | | Immunogen | Synthetic peptide corresponding to aa1-12 of human Cullin 3 at N-terminal (KLH). | | Specificity | Recognizes human Cullin 3. Species sequence homology: Mouse. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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