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You are here:Home » Antibodies » Abs to Cullin » Anti -Cullin 5 (CUL-5)

Anti -Cullin 5 (CUL-5)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Serum E B
Cullins (1, 2, 3, 4a, 5 and 7) are a family of proteins that assemble a large number of ubiquitin ligases to catalyse polyubiquitiation, as well as binding to various specific factors to recruit substrates. Cullin 5 (CUL 5) is a component of E3 ubiquitin ligase complexes and it is involved in proteosomal degradation of p53/TP53 stimulated by adenovirus E1B-55 kD protein. It may also form a cell surface vasopresin receptor and it may play a role in brast tumorigenesis.
Catalog #C7949-21N1
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionELISA: 1:2000-1:10,000
Western Blot: 1:500-1:1,000
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
HostRabbit
SourceHuman
ConcentrationNot determined
FormSupplied as a liquid, 0.01% sodium azide.
PurityPurified by delipidation and defibrination.
ImmunogenSynthetic peptide, SNLLKNKGSLQFEDK, corresponding to aa4-18 of human Cul5, N-terminus (KLH).
SpecificityRecognizes human Cullin 5 at ~90.9kD.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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