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You are here:Home » Antibodies » Antibodies-Cullin » Anti -Cullin 7 (CUL-7, p185, KIAA0076, Cullin homolog 7, p180)

Anti -Cullin 7 (CUL-7, p185, KIAA0076, Cullin homolog 7, p180)


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Clone Host Grade Applications
Polyclonal Rabbit Serum E B
Cullins (1, 2, 3, 4a, 5 and 7) are a family of proteins that assemble a large number of ubiquitin ligases to catalyse polyubiquitiation, as well as binding to various specific factors to recruit substrates. Cullin 7 (CUL 7) is a component of SCF-like E3 ubiquitin ligase complex and may play a role in the degradation of proteins involved in endothelial proliferation and/or differentiation. Cullin 7 is a new oncogene that cooperates with Myc in transformation by blocking Myc-induced apoptosis in a p53-dependent manner.
Catalog #C7949-22G
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionELISA: 1:2000-1:10,000
Western Blot: 1:500-1:1000
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
ConcentrationNot determined
FormSupplied as a liquid, 0.01% sodium azide.
PurityPurified by delipidation and defibrination.
ImmunogenSynthetic peptide, RSRGVPYASCTATQSFSTFR, corresponding to aa1679-1698 of human Cul7, C-terminus (KLH).
SpecificityRecognizes human Cullin 7 at ~191.2kD. Species Crossreactivity: mouse.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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