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You are here:Home » Growth Factors, Cytokines » Growth Factors-CTGF » CTGF, Recombinant, Human (Connective Tissue Growth Factor, CCN2, Hypertrophic Chondrocyte-specific Gene Product 24, Hcs24, Insulin-like Growth Factor-Binding Protein 8, IGFBP8, MGC102839, NOV2)

CTGF, Recombinant, Human (Connective Tissue Growth Factor, CCN2, Hypertrophic
Chondrocyte-specific Gene Product 24, Hcs24, Insulin-like Growth Factor-Binding Protein 8,
IGFBP8, MGC102839, NOV2)

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Specifications

CTGF (connective tissue growth factor) is a heparin-binding pleiotropic growth factor and member of the CCN family of secreted cysteine rich regulatory proteins, which interacts with other growth factors including transforming growth factor beta (TGF-beta), vascular endothelial growth factor (VEGF) and bone morphogenetic proteins (BMPs).
Catalog #C7978-25H
CTGF promotes the adhesion of epithelial cells and fibroblasts, stimulates integrin expression, and promotes endothelial cell survival, migration and adhesion, implicating CTGF in angiogenesis. CTGF is involved in chondrogenesis and potentially skeletogenesis, induces extracellular matrix formation and has also been implicated in wound healing.
SourceRecombinant corrresponding to human CTGF expressed in E.coli.
Molecular Weight~11.2kD (98aa residues)
ActivityDetermined by the dose-dependent stimulation of the proliferation of HUVEC cells. The expected ED50 for this effect is 1.0-2.0 µg/ml.
Endotoxin 1EU/ug
ApplicationsSuitable for use in ELISA, Functional Assays and Western Blot. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and Stability
Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with 200ul sterile dH2O. Aliquot and store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
SourceRecombinant, expressed in E. coli
PurityPurified: ~95% (SDS PAGE/HPLC)
FormSupplied as a lyophilized powder in 10mM sodium acetate. Preservative free. Reconstitute with 200ul sterile dH2O.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesHypertrophic Chondrocyte-specific Protein 24


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