You are here:Home
»
Biochemicals
»
Biochem-Inhibitors
»
Curcumin (Curcuma Longa, 1,7-bis(4-Hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione, Diferuloylmethane)
Curcumin (Curcuma Longa, 1,7-bis(4-Hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione,
Diferuloylmethane)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Cell-permeable. An antioxidant and dual inhibitor of 5-lipoxygenase (IC50=8uM) and cyclooxygenase (COX) (IC50=52uM). Also inhibits glutathione S-transferase, induction of nitric oxide (NO) in activated macrophages and inhibits EGF-induced tyrosine phosphorylation of EGF receptors. Also shown to be a p300/CREB-binding protein-specific inhibitor of histone acetyltransferase, inhibiting the acetylation of histones H3 and H4 with an IC50 of ~25uM. Does not affect p300/CREB binding protein-associated factor (PCAF). | | | Catalog # | C7980-80 | | Solubility | DMSO (25mg/ml) or EtOH (10mg/ml) | | Molecular Weight | ~368.38 | | CAS Number | 458-37-7 | | Molecular Formula | C H O | | Molecular Weight | ~368.38 | | Purity | ~98% (¹H NMR) | | Concentration | Not determined | | Form | Supplied as a orange-yellow solid. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
External Links
|
