Anti -CX3CR1 (Beta Chemokine Receptor-like 1, CCRL1, Chemokine C-X3-C Motif Receptor 1, CX3C Chemokine Receptor 1, C-X3-C CKR-1, CX3C CKR-1, CMK-BRL-1, CMKBLR1, CMKDR1, Fractalkine Receptor, GPR13, GPRV28, V28)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
B IH FC N |
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| Fractalkine, also termed neurotactin, is a membrane-bound CX3C chemokine. Rat CX3CR1, also named RBS11, was first cloned from rat brainstem, pituitary and/or spinal cord cDNA libraries. A G-protein-coupled seven-transmembrane domain receptor, it was recently identified to serve as fractalkine receptor. The human equivalent receptor is known as V28, which has been shown to mediate both the adhesive and migratory functions of fractalkine. Fractalkine and CX3CR1 represent new types of leukocyte trafficking regulators. | | | Catalog # | C8299-01A | | Applications | Suitable for use in Western Blot, Flow Cytometry, Immunohistochemistry and Neutralization. Other applications not tested. | | Recommended Dilution | Western Blot: 1:1000-1:2000 | | Flow Cytometry: 1:100-1:300 | | Immunohistochemistry: 1:100-1:300 | | Neutralization: calcium mobilization assays | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Rat | | Concentration | ~1mg/ml | | Form | Supplied as a liquid, 0.05% sodium azide. | | Purity | Purified by Protein A affinity chromatography. | | Immunogen | E. coli-expressed rat CX3CR1 amino terminal domain. | | Specificity | Recognizes recombinant and natural rat CX3CR1. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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Download Specifications for Anti -CX3CR1 (Beta Chemokine Receptor-like 1, CCRL1, Chemokine C-X3-C Motif Receptor 1, CX3C Chemokine Receptor 1, C-X3-C CKR-1, CX3C CKR-1, CMK-BRL-1, CMKBLR1, CMKDR1, Fractalkine Receptor, GPR13, GPRV28, V28) |
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