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You are here:Home » Antibodies » Abs to G Protein Receptors » Anti -CX3CR1 (CX3C Chemokine Receptor 1, C-X3-C CKR-1, CX3CR1, Beta Chemokine Receptor-like 1, CMK-BRL-1, CMK-BRL1, Fractalkine Receptor, G-protein Coupled Receptor 13, V28, CMKBRL1, GPR13)

Anti -CX3CR1 (CX3C Chemokine Receptor 1, C-X3-C CKR-1, CX3CR1, Beta Chemokine
Receptor-like 1, CMK-BRL-1, CMK-BRL1, Fractalkine Receptor, G-protein Coupled Receptor 13,
V28, CMKBRL1, GPR13)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B
CX3CR1 is one of the chemokine receptors that are required as coreceptors for HIV infection. The genes encoding human, mouse, and rat CX3CR1 were cloned and designated V28 and CMKBRL1, CX3CR1, and RBS11, respectively,. The encoded seven transmembrane protein was recently identified as the receptor for a novel transmembrane molecule, fractalkine, and renamed CX3CR1. Recently, CX3CR1 was found to serve as a coreceptor for HIV-1 and HIV-2 envelope fusion and virus infection, which can be inhibited by fractokine. CX3CR1 mediates leukocyte migration and adhesion. CX3CR1 is expressed in a variety of human tissues and cell lines.
Catalog #C8299-02B
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 1:500
Optimal dilutions to be determined by the researcher.
Positive ControlTHP-1 cell lysate
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, 0.02% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to human CX3CR1, EL.
SpecificityRecognizes human CX3CR1.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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