You are here:Home
»
Antibodies
»
Abs to Growth Factors, Cytokines
»
Anti -CXCR1 (C-X-C Chemokine Receptor 1)
Anti -CXCR1 (C-X-C Chemokine Receptor 1)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
B |
|
| Chemokine receptors belong to the superfamily of G protein-coupled receptors, which regulate the trafficking and activation of leukocytes and operate as co-receptors in the entry of HIV-1. CXC chemokine receptor 1 (CXCR1) is one of the important receptors for CXC chemokines with ELR motif, of with interleukin 8 (IL-8; CXCL8) is representative. CXCR1 expression plays an important role in many inflammatory processes. | | | Catalog # | C8348-10 | | Applications | This antibody can be used for detection of human CXCR1 expression by Western blot. A band of approx. size 38 kD should be detected. It will cross-react with mouse CXCR1. Western blot analysis of 15 ug of whole cell lysate from Raw cells at 2ug/ml dilution. | | Recommended Dilution | Western blot: 1-3ug/ml | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Freeze at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | ~0.5mg/ml | | Form | Supplied as a liquid in PBS, 0.2% gelatin, 0.05% sodium azide. | | Purity | Purified by Protein G affinity chromatography. | | Immunogen | Synthetic peptide of human CXCR1 protein. | | Specificity | Chemokine receptors belong to the superfamily of G protein-coupled receptors, which regulate the trafficking and activation of leukocytes and operate as co-receptors in the entry of HIV-1. CXC chemokine receptor 1 (CXCR1) is one of the important receptors for CXC chemokines with ELR motif, of with interleukin 8 (IL-8; CXCL8) is representative. CXCR1 expression plays an important role in many inflammatory processes. | | | Applications | | | This antibody can be used for detection of human CXCR1 expression by Western blot. A band of approx. size 38 kD should be detected. It will cross-react with mouse CXCR1. Western blot analysis of 15 ug of whole cell lysate from Raw cells at 2ug/ml dilution. | | | Recommended Dilution | | | Western blot | 1-3ug/ml | | | Storage and Stability | | | It is supplied as Protein G purified IgG fraction. Store at 4oC, stable for 6 months. For long-term storage, store at -20oC. | | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
External Links
|
