Anti -CXCR3 (C-X-C Chemokine Receptor Type 3, Chemokine (C-X-C Motif) Receptor 3, CXCR-3,
CXC-R3, CD182, CD183, CKR-L2, CMKAR3, G Protein-coupled Receptor 9, GPR9,
Interferon-inducible Protein 10 Receptor, IP-10 Receptor, IP10-R, MigR, Mig-R)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
IH |
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| CXCR3, a Chemokine Receptor, is highly similar to the interleukine 8B receptor and has been shown to mediate recruitment of T cells to sites of inflammation and retention of T-cells in the inflamed CNS. CXCR3 has been suggested to be the principal inflammatory chemokine receptor involved in intrathecal accumulation of T-cells in multiple sclerosis and diabetes. It is expressed on malignant B cells in chronic lymphoproliferative disorders (Jones et al., 2000). An alternatively spliced isoform, CXCR3B, has recently been identified (Lasagni et al. 2003). CXCR3 expression has been documented in the brain, lymphoid and other peripheral tissues, and in diseasess including atheroslerosis, Alzheimer's, multiple sclerosis, rheumatoid arthritis, lymphomas, asthma, neoplasms, leukemia, and inflammatory conditions of various organs. | | | Catalog # | C8349-03D | | Applications | Suitable for use in Immunohistochemistry. Other applications not tested. | | Recommended Dilutions | Immunohistochemistry (Paraffin): 16ug/ml | | Optimal dilutions to be determined by the researcher. | | Positive Control | Human tonsil | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | ~1mg/ml | | Form | Supplied as a liquid in PBS, pH 7.7, 0.01% sodium azide. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Synthetic peptide corresponding to the C-terminal domain of human CXCR3. | | Specificity | Recognizes human CXCR3. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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Download Specifications for Anti -CXCR3 (C-X-C Chemokine Receptor Type 3, Chemokine (C-X-C Motif) Receptor 3, CXCR-3, CXC-R3, CD182, CD183, CKR-L2, CMKAR3, G Protein-coupled Receptor 9, GPR9, Interferon-inducible Protein 10 Receptor, IP-10 Receptor, IP10-R, MigR, Mig-R) |
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