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You are here:Home » Antibodies » Abs to Growth Factors, Cytokines » Anti -CXCR3 (C-X-C Chemokine Receptor Type 3, CXC-R3, CXCR-3, CKR-L2, G Protein-coupled Receptor 9, Interferon-inducible Protein 10 Receptor, IP-10 Receptor, CD183, GPR9)

Anti -CXCR3 (C-X-C Chemokine Receptor Type 3, CXC-R3, CXCR-3, CKR-L2, G Protein-coupled
Receptor 9, Interferon-inducible Protein 10 Receptor, IP-10 Receptor, CD183, GPR9)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B
Chemokines play important roles in inflammation and critical for the recruitment of effector immune cells to sites of infection. Historically, CD183 was the third CXC chemokine receptor discovered and therefore, commonly designated as CXCR3. Binding of chemokines to CD183 induces cellular responses that are involved in leukocyte traffic, most notably integrin activation, cytoskeletal changes and chemotactic migration. The CXC chemokine receptor (CXCR) 3, a G-protein-coupled 7-transmembrane receptor, is expressed at high levels on activated and memory T cells, B cells, natural killer cells, and plasmacytoid monocytes.
Catalog #C8349-05
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 1-3ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. 
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in PBS, 0.1mg/ml BSA, 0.02% sodium azide.
PurityPurified by Protein G affinity chromatography.
ImmunogenSynthetic peptide corresponding to aa 338-349 of human CXCR3.
SpecificityRecognizes human CXCR3. Species Crossreactivity: Mouse
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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