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You are here:Home » Antibodies » Abs to Growth Factors, Cytokines » Anti -CCR4 (C C chemokine receptor type 4, C C CKR 4, CC CKR 4, CCR 4, Chemokine (CC motif) receptor 4, chemokine C C motif receptor 4, ChemR13, CKR4, CMKBR 4, CMKBR4, HGCN 14099, K5 5, MGC88293)

Anti -CCR4 (C C chemokine receptor type 4, C C CKR 4, CC CKR 4, CCR 4, Chemokine (CC
motif) receptor 4, chemokine C C motif receptor 4, ChemR13, CKR4, CMKBR 4, CMKBR4, HGCN
14099, K5 5, MGC88293)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E B IH IC FC
Chemokine receptors are G protein-coupled receptors (GPCRs) that play a key role in inflammation and are characterized by similar sequences with a 4 cysteine motif. The C-C receptors are important in the function of T cell chemotaxis and migration of phagocytic cells to sites of inflammation. Receptors for the C-C chemokine family include CCR-1, CCR-2A, CCR-3, CCR-4, CCR-5 and the Duffy blood group antigen.
Catalog #C8350-01B
Cellular Localization Cell membrane
Positive Control Human peripheral blood cells or paraffin sections of spleen.
ApplicationsSuitable for use in Flow Cytometry, ELISA, Western Blot, Immunohistochemistry (paraffin-embedded sections) and Immunocytochemistry. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostGoat
SourceHuman
ConcentrationAs reported
Form10 mM potassium dibasic phosphate, 140 mM sodium chloride, [pH7.2]
PurityPurified by immunoaffinity chromatography.
ImmunogenA synthetic peptide [SNYYLYESIPKPCTKEGIKAFGE] corresponding to amino acids 17-39 of the extracellular domain of human CCR4.
SpecificityPeptide sequence is < 50% identical to other human chemokine receptors in this region. Species Crossreactivity: Human. Other species have not been tested.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesC C chemokine receptor type 4, C C CKR 4, CC CKR 4, CCR 4, Chemokine (CC motif) receptor 4, chemokine C C motif receptor 4, ChemR13, CKR4, CMKBR 4, CMKBR4, HGCN 14099, K5 5, MGC88293


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