Anti -CXCR4 (Fusin, LESTR, HUMSTR, C-X-C Chemokine Receptor 4, CD184)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Affinity Purified |
E IH FC |
|
| CXCR4, also known as fusin, is a 7TM G protein-linked chemokine receptor. CXCR4 is expressed on B cells, monocytes, CD4 + T cells, colonic epithelial cells, and astrocytes and binds SDF-1/CXCL12. CXCR4 is upregulated on mammary tumors. CXCR4, in cooperation with CD134 and heparan sulfate proteoglycans, functions as a co-receptor for feline immunodeficiency virus (FIV) entry into cells. Feline CXCR4 shares 97%, 95%, 88%, and 90% aa sequence identity with canine, human, mouse, and rat CXCR4, respectively. | | | Catalog # | C8350-06C | | Applications | Suitable for use in Flow Cytometry, Immunohistochemistry and ELISA. Other applications not tested. | | Recommended Dilution | Flow Cytometry: 25ug/ml | | Immunohistochemistry: 25ug/ml | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | Lyophilized powder may be stored at 4°C for short-term only. Reconstitute to nominal volume by adding sterile 40-50% glycerol and store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG2a | | Clone No | 7H160 | | Host | Mouse | | Source | Feline | | Concentration | As reported | | Form | Supplied as a lyophilized powder from a 0.2um filtered solution in PBS, 5% trehalose. Reconstitute with 1ml sterile ddH2O or sterile 40-50% glycerol. | | Purity | Purified by Protein G affinity chromatography. | | Immunogen | HEK293 cells transfected with feline CXCR4 (Accession # P56498) | | Specificity | Recognizes feline CXCR4. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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