Login

Forgot your password?
New User?
Remember me
banner banner

You are here:Home » Antibodies » Abs to Growth Factors, Cytokines » Anti -CXCR4 (Fusin, LESTR, HUMSTR, C-X-C Chemokine Receptor 4, CD184)

Anti -CXCR4 (Fusin, LESTR, HUMSTR, C-X-C Chemokine Receptor 4, CD184)

Pricing

  For pricing information, USA customers sign in.
  Outside USA? Please contact your distributor for pricing.

Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified IH FC IF
Viral entry into target cells is mediated through a complex interaction between the viral envelope protein and specific cellular receptors. The CD4 glycoprotein is the primary receptor for human HIV types 1 and 2. However, one or more cellular coreceptors are also needed for viral entry. CXCR4 has been identified as a co-receptor for HIV type 1. T lymphocytes and macrophages in both lymphoid and non-lymphoid tissues are the major cell populations expressing CXCR4. CXCR4, also known as Chemokine (C-X-C motif) Receptor 4 or CD184, is a receptor for the CXC chemokine stromal cellderived factor-1 (SDF-1) and is involved in cardiogenesis, blood vessel formation, and cerebellular development. CXCR4 has been reported to be ubiquitously expressed in blood and tissue cells.
Catalog #C8350-07
ApplicationsSuitable for use in Immunohistochemistry, Immunofluorescence and Flow Cytometry. Other applications have not been tested.
Recommended DilutionImmunohistochemistry: 10ug/ml
Immunofluorescence: 10ug/ml. Do not use cells fixed in acetone or methanol. 3% paraformaldehyde has been shown to give optimal results.
Flow Cytometry: 2-5ug/ml
Optimal dilutions to be determined by the researcher.
Positive ControlsHuman lymphoid cell lines, human liver and brain tissues.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG2a
Clone No6A57
HostMouse
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in PBS, pH 7.4, 0.1% sodium azide.
PurityPurified by Protein A chromatography
ImmunogenCP-MAC infected Human Sup-T1 cells.
SpecificityRecognizes human CXCR4 protein.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


External Links