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You are here:Home » Antibodies » Abs to Growth Factors, Cytokines » Anti -CXCR5 (C-X-C Chemokine Receptor 5)

Anti -CXCR5 (C-X-C Chemokine Receptor 5)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified FC
This gene was identified as a gene specifically expressed in Burkitt's lymphoma and lymphatic tissues. The protein encoded by this gene is predicted to be a seven transmembrane G protein- coupled receptor and belongs to the CXC chemokine receptor family. BLC, a B-lymphocyte chemoattractant, was identified to be a specific ligand for this receptor. Studies of this gene and its mouse conterpart strongly suggest the essential function of this gene in B cell migration and localization within specific anatomic compartments, such as follicles in lymph nodes as well as in spleen. Two alternatively spliced variants of this gene exist.
Catalog #C8375-10A
ApplicationsSuitable for use in Flow Cytometry. Other applications not tested.
Recommended DilutionsFlow Cytometry: 10-25mg/ml for 10e5 cells. Using human peripheral blood mononuclear cells expressing CXCR5.
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG2b
Clone No8J1098
HostMouse
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in PBS. No preservative.
PurityPurified by Protein G affinity chromatography.
ImmunogenHuman CXCR5 (BLR1) transfected NSO mouse myeloma cells. Cellular Localization: Integral membrane protein
SpecificityRecognizes human CXCR5 (BLR1) transfected cells but not with the parent cell line by Flow Cytometry. Shows no crossreactivity with human CXCR2, CXCR3 and CXCR4.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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