Anti -CXCR6 (C-X-C Chemokine Receptor Type 6, Chemokine (C-X-C motif) Receptor 6, CXCR-6,
CXC-R6, BONZO, CD186, CDw186, G-protein Coupled Receptor Bonzo, G-protein Coupled Receptor
STRL33, STRL33, TYMSTR)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
IH |
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| Coreceptor usage of primary Human immunodeficiency virus type 1 (HIV-1) isolates varies according to biological phenotype. The chemokine receptors CCR5 and CXCR4 are the major coreceptors that, together with CD4, govern HIV-1 entry into cells. Some HIV-1, HIV-2, and SIV isolates of different genetic subtypes and biological phenotypes use other chemokine receptors, such as CXCR6, a T-lymphocyte-expressed seven-transmembrane domain receptor that mediates fusion, entry, and trafficking of tumor-infiltrating lymphocytes. CXCR6 has been identified in Human blood (T-lymphocytes, activated peripheral blood lymphocytes, monocyte-derived dendritic cells, primitive cord blood cells), placental trophoblasts, T-lymphocytes and dendritic cells in the skin, lymphoid tissues, and in fetal brain astrocytes. ESTs have been isolated from Human normal placenta, liver/spleen, and pregnant uterus libraries, and Human cancer kidney and uterus libraries. | | | Catalog # | C8375-15 | | Applications | Suitable for use in Immunohistochemistry. Other applications not tested. | | Recommended Dilution | Immunohistochemistry (paraffin): 6.8ug/ml | | Optimal dilutions to be determined by the researcher. | | Positive Control | Human Tonsil, Interfollicular zone | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | ~1mg/ml | | Form | Supplied as a liquid in PBS, pH 7.7, 0.1% sodium azide. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Synthetic peptide corresponding to the 2nd cytoplasmic domain of human CXCR6. | | Specificity | Recognizes human CXCR6. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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Download Specifications for Anti -CXCR6 (C-X-C Chemokine Receptor Type 6, Chemokine (C-X-C motif) Receptor 6, CXCR-6, CXC-R6, BONZO, CD186, CDw186, G-protein Coupled Receptor Bonzo, G-protein Coupled Receptor STRL33, STRL33, TYMSTR) |
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