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You are here:Home » Antibodies » Abs to G Protein Receptors » Anti -CXCR6 (C-X-C Chemokine Receptor Type 6, Chemokine (C-X-C motif) Receptor 6, CXCR-6, CXC-R6, BONZO, CD186, CDw186, G-protein Coupled Receptor Bonzo, G-protein Coupled Receptor STRL33, STRL33, TYMSTR)

Anti -CXCR6 (C-X-C Chemokine Receptor Type 6, Chemokine (C-X-C motif) Receptor 6, CXCR-6,
CXC-R6, BONZO, CD186, CDw186, G-protein Coupled Receptor Bonzo, G-protein Coupled Receptor
STRL33, STRL33, TYMSTR)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified IH
Coreceptor usage of primary Human immunodeficiency virus type 1 (HIV-1) isolates varies according to biological phenotype. The chemokine receptors CCR5 and CXCR4 are the major coreceptors that, together with CD4, govern HIV-1 entry into cells. Some HIV-1, HIV-2, and SIV isolates of different genetic subtypes and biological phenotypes use other chemokine receptors, such as CXCR6, a T-lymphocyte-expressed seven-transmembrane domain receptor that mediates fusion, entry, and trafficking of tumor-infiltrating lymphocytes. CXCR6 has been identified in Human blood (T-lymphocytes, activated peripheral blood lymphocytes, monocyte-derived dendritic cells, primitive cord blood cells), placental trophoblasts, T-lymphocytes and dendritic cells in the skin, lymphoid tissues, and in fetal brain astrocytes. ESTs have been isolated from Human normal placenta, liver/spleen, and pregnant uterus libraries, and Human cancer kidney and uterus libraries.
Catalog #C8375-15A
ApplicationsSuitable for use in Immunohistochemistry. Other applications not tested.
Recommended DilutionImmunohistochemistry (paraffin): 16ug/ml
Optimal dilutions to be determined by the researcher.
Positive ControlHuman Tonsil, Interfollicular zone
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in PBS, pH 7.7, 0.1% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to the C-terminal domain of human CXCR6.
SpecificityRecognizes human CXCR6.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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