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You are here:Home » Antibodies » Abs to G Protein Receptors » Anti -CXCR7 (C-X-C Chemokine Receptor Type 7, CXC-R7, CXCR-7, Chemokine Orphan Receptor 1, G-protein Coupled Receptor 159, G-protein Coupled Receptor RDC1 Homolog, RDC-1, CMKOR1, GPR159, RDC1) (Carboxyfluorescein)

Anti -CXCR7 (C-X-C Chemokine Receptor Type 7, CXC-R7, CXCR-7, Chemokine Orphan Receptor 1,
G-protein Coupled Receptor 159, G-protein Coupled Receptor RDC1 Homolog, RDC-1, CMKOR1,
GPR159, RDC1) (Carboxyfluorescein)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified FC
CXCR7 can bind with high-affinity to CXCL12/SDF-1 and CXCL11/I-TAC, and is also a co-receptor for several HIV and SIV strains. Reports of mRNA levels and/or protein expression indicate that CXCR7 occurs on a wide variety of tissues and cells including monocytes, B cells, T cells and mature dendritic cells. In contrast, receptor level and ligand binding analyses indicate that surface expression of CXCR7 is restricted to tumor cells, activated endothelial cells, fetal liver cells, and a few other cell types. The basis of these inconsistent observations is not known but may be attributed to cell context and the use of different antibodies that may recognize different epitopes.
Catalog #C8376-25F
ApplicationsSuitable for use in Flow Cytometry. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
HybridomaFusion of a mouse myeloma with B cells obtained from a mouse immunized with NS0 cells transfected with human CXCR7.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG2A
Clone No10K17
HostMouse
SourceHuman
Concentration100 Tests/ml
FormSupplied as a liquid in 1ml saline, 0.5% BSA, 0.1% sodium azide. Labeled with Carboxyfluorescein.
PurityPurified by Protein G affinity chromatography.
ImmunogenNS0 cells transfected with human CXCR7 (Accession #P25106).
SpecificityRecognizes human CXCR7.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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