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You are here:Home » Antibodies » Antibodies-Cyclin » Anti -Cyclin C

Anti -Cyclin C


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Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B IP IF
Cyclin C was originally identified by a genetic screen for human and Drosophila cDNAs that
complement a triple knockout of the CLN genes in Saccharomyces cerevisiae. Cyclin C interacts both in vivo and in vitro with cdk8. This complex is reported to control RNA polymerase II function.
Catalog #C8453-32
ApplicationsSuitable for use in Immunofluorescence, ELISA, Western Blot and Immunoprecipitation. Other applications not tested.
Recommended DilutionWestern Blot: 1:100-1:200
Immunoprecipitation: 10ul/mg
Optimal dilutions to be determined by the researcher.
Positive ControlHeLa or NIH-3T3 cells
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.4, 0.2% BSA, 0.09% sodium azide.
PurityPurified by Protein A affinity chromatography.
ImmunogenA synthetic peptide corresponding to aa 290-303 (Cys-QGPNGSQNSSYSQS) from the C-terminus of human cyclin C (KLH).
SpecificityRecognizes human cyclin C at ~31-32kD. Species Crossreactivity: human, canine, mouse, and rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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