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Abs to Cyclin
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Anti -Cyclin D1 (CCND1, B-cell Lymphoma 1 Protein, BCL-1 Oncogene, BCL1, D11S287E, G1/S-specific Cyclin-D1, PRAD1 Oncogene, U21B31)
Anti -Cyclin D1 (CCND1, B-cell Lymphoma 1 Protein, BCL-1 Oncogene, BCL1, D11S287E,
G1/S-specific Cyclin-D1, PRAD1 Oncogene, U21B31)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Rabbit |
Supernatant |
IH |
|
| The cyclin D proteins function predominantly by regulating cyclin dependent kinase activity in the G1 phase of the cell cycle. Cyclin D1 expression has been shown to be amplified in tumors such as breast cancer and mantle cell lymphoma. This antibody will help detect the presence of cyclin D1 in normal and uncharacterized tissues. | | | Catalog # | C8454-07C | | Applications | Suitable for use in Immunohistochemistry. Other applications not tested. | | Recommended Dilution | Immunohistochemistry: 1:50-1:100 for 30 mins. at RT | | Optimal dilutions to be determined by the researcher. | | Positive Control | | | Breast carcinoma or mantle cell lymphoma. Nuclear staining pattern. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG | | Clone No | SP4 | | Host | Rabbit | | Source | Human | | Concentration | Not determined | | Form | Supplied as a liquid in 15mM sodium azide. | | Purity | Supernatant | | Immunogen | Synthetic peptide corresponding to a region of the C-terminus of the human cyclin D1 molecule. | | Specificity | Recognizes human Cyclin D1. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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