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You are here:Home » Antibodies » Antibodies-Cyclin » Anti -Cyclin D2

Anti -Cyclin D2


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Clone Host Grade Applications
Monoclonal Mouse Supernatant B IP IC IF
Cyclins are regulatory subunits of the cyclin-dependent kinases (cdk), which control transition at different specific phases of the cell cycle. In mammalian cells, cyclin D2 plays a critical role in G1 to S transition and is a putative proto-oncogene. Cyclin D2 can phosphorylate pRB when associated with cdk4 and/or cdk6.
Catalog #C8454-12E
ApplicationsSuitable for use in Immunofluorescence, Immunoblotting, Immunoprecipitation, Immunocytochemistry. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
Clone No9L134
ConcentrationNot determined
FormSupplied as a liquid in 0.09% sodium azide.
ImmunogenRecombinant human Cyclin D2.
SpecificityRecognizes human Cyclin D2. Known to interact with Cdk4 in the G1 phase of the cell cycle. Does not cross-react with cyclin D1 and cyclin D3. Species Crossreactivity: mouse.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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