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You are here:Home » Antibodies » Abs to Cyclin » Anti -CCNDBP1 (Cyclin D type binding protein 1, GCIP, Grap2 cyclin interacting protein, MAID)

Anti -CCNDBP1 (Cyclin D type binding protein 1, GCIP, Grap2 cyclin interacting protein,
MAID)

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E B
This gene was identified by the interaction of its gene product with Grap2, a leukocyte specific adaptor protein important for immune cell signaling. The protein encoded by this gene was shown to interact with cyclin D. Transfection of this gene in cells was reported to reduce the phosphorylation of Rb gene product by cyclin D dependent protein kinase, and inhibit E2F1 mediated transcription activity. This protein was also found to interact with helix loop helix protein E12 and is thought to be a negative regulator of liver specific gene expression. Two alternatively spliced variants, which encode distinct isoforms, have been reported
Catalog #C8456
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in TBS, pH 7.2, 0.5% BSA.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide: NRIKELTQSELEL representing the C-terminus of the human protein (residues 348-360), according to NP_036274; NP_411241.
SpecificitySpecies Crossreactivity: Expected to crossreact with Human due to sequence homology.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesCyclin D type binding protein 1, GCIP, Grap2 cyclin interacting protein, MAID


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