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You are here:Home » Biochemicals » Biochem-Antibiotics » Cycloheximide



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Cycloheximide is an antibiotic produced by S. griseus. Its main biological activity is translation inhibition in eukaryotes, resulting in inhibition of protein synthesis leading to cell growth, cell arrest and cell death. CHX is widely used for selection of CHX resistant yeast and fungi strains; controlled inhibition of protein synthesis for detection of short-lived proteins and super-induction of protein expression; apoptosis induction or facilitation of apoptosis induction of death receptors.
Catalog #C8500
Purity ~94-96%
Appearance Off-white crystalline powder
Solubility (2.1g/100ml)Soluble in Chloroform, Acetone and Methanol; slightly soluble in water
Storage and StabilityLyophilized powder may be stored at 4°C. Stable for 12 months at 4°C.
CAS Number66-81-9
Molecular FormulaC15H23NO4
Molecular Weight281.35
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesActidione; Naramycin; 4-[2-(3,5-Dimethyl-2- oxocyclohexyl)-2-hydroxyethyl]-2,6-piperidinedione

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