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Specifications

Cycloheximide is an antibiotic produced by S. griseus. Its main biological activity is translation inhibition in eukaryotes, resulting in inhibition of protein synthesis leading to cell growth, cell arrest and cell death. CHX is widely used for selection of CHX resistant yeast and fungi strains; controlled inhibition of protein synthesis for detection of short-lived proteins and super-induction of protein expression; apoptosis induction or facilitation of apoptosis induction of death receptors.
Catalog #	C8500-10
	Prepared from C8500 Cycloheximide
Specific Rotation (C=1, CHCl3)	-25° to -32°
Working Concentration	30-50ug/ml.
Appearance	Colorless to light yellow, clear, complete.
Storage and Stability	For long term storage, aliquot and store at -20°C. Aliquots are stable for 12 months at -20°C.
CAS Number	66-81-9
Molecular Formula	C15H23NO4
Molecular Weight	281.35
Source	S. griseus
Purity	~98%
Concentration	50mg/ml
Form	Supplied as a sterile-filtered (0.2um) liquid in 95% ethanol.
Important Note	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate names	Actidione; Naramycin; 4-[2-(3,5-Dimethyl-2-oxocyclohexyl)-2-hydroxyethyl]-2,6-piperidinedione