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You are here:Home » Antibodies » Abs to Cyclophilin » Anti -Cyclophilin A (Peptidyl-prolyl Cis-trans Isomerase A, PPIase A, Rotamase A, PPIA, Cyclosporin A-binding Protein, CYPA)

Anti -Cyclophilin A (Peptidyl-prolyl Cis-trans Isomerase A, PPIase A, Rotamase A, PPIA,
Cyclosporin A-binding Protein, CYPA)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E B
PPIA is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein is a cyclosporin binding-protein and may play a role in cyclosporin A-mediated immunosuppression. The protein can also interact with several HIV proteins, including p55 gag, Vpr, and capsid protein, and has been shown to be necessary for the formation of infectious HIV virions.
Catalog #C8850-01H
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionELISA: 1:8000
Western Blot: 0.1-0.3ug/ml, observed in Human Lymph Node lysates on ~18kD bands
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to C-ERFGSRNGKTSKK, from human PPIA, at the internal region of the protein (NP_066953.1).
SpecificityRecognizes human PPIA. Species sequence homology: Bovine, canine, mouse, porcine and rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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