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You are here:Home » Antibodies » Abs to Cyclophilin » Anti -CYPC (Peptidyl-prolyl Cis-trans Isomerase C, PPIase C, Cyclophilin C, Rotamase C, PPIC)

Anti -CYPC (Peptidyl-prolyl Cis-trans Isomerase C, PPIase C, Cyclophilin C, Rotamase C,
PPIC)

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Specifications

Clone Host Grade Applications
Polyclonal Sheep Affinity Purified B
Cyclophilin C (CyPC, also Rotamase C and peptidyl-prolyl cis-trans isomerase C) is a 17-23kD member of the cyclophilin-type PPIase family of molecules. It is known to be a Mg2+-dependent intracellular enzyme that can degrade DNA into 50 kb fragments. It also has the potential to interact extracellularly with OPN and activate CD147/EMMPRIN. Human CyPC is 212aa in length. It contains one cyclophilin type PPIase domain (aa41-198). Over aa31-182, human CyPC shares 95aa identity with mouse CyPC, 59%, 79%, 58% aa identity with human CyPA, B and D, respectively.
Catalog #C8855-19
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 1ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostSheep
SourceHuman
ConcentrationNot determined
FormSupplied as a lyophilized powder in PBS, Trehalose. Reconstitute with sterile PBS to 200ug/ml.
PurityPurified by immunoaffinity chromatography.
ImmunogenRecombinant corresponding to aa31-182 from human Cyclophilin C expressed in E. coli (P45877).
SpecificityRecognizes human Cyclophilin C. Species sequence homology: recombinant human Cyclophilin A, rhCyclophilin A-Like 4, rhCyclophilin B, rhCyclophilin E and rhCyclophilin F (1%).
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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