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Abs to Cyclophilin
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Anti -CYPC (Peptidyl-prolyl Cis-trans Isomerase C, PPIase C, Cyclophilin C, Rotamase C, PPIC)
Anti -CYPC (Peptidyl-prolyl Cis-trans Isomerase C, PPIase C, Cyclophilin C, Rotamase C,
PPIC)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Sheep |
Affinity Purified |
B |
|
| Cyclophilin C (CyPC, also Rotamase C and peptidyl-prolyl cis-trans isomerase C) is a 17-23kD member of the cyclophilin-type PPIase family of molecules. It is known to be a Mg2+-dependent intracellular enzyme that can degrade DNA into 50 kb fragments. It also has the potential to interact extracellularly with OPN and activate CD147/EMMPRIN. Human CyPC is 212aa in length. It contains one cyclophilin type PPIase domain (aa41-198). Over aa31-182, human CyPC shares 95aa identity with mouse CyPC, 59%, 79%, 58% aa identity with human CyPA, B and D, respectively. | | | Catalog # | C8855-19 | | Applications | Suitable for use in Western Blot. Other applications not tested. | | Recommended Dilution | Western Blot: 1ug/ml | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Sheep | | Source | Human | | Concentration | Not determined | | Form | Supplied as a lyophilized powder in PBS, Trehalose. Reconstitute with sterile PBS to 200ug/ml. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Recombinant corresponding to aa31-182 from human Cyclophilin C expressed in E. coli (P45877). | | Specificity | Recognizes human Cyclophilin C. Species sequence homology: recombinant human Cyclophilin A, rhCyclophilin A-Like 4, rhCyclophilin B, rhCyclophilin E and rhCyclophilin F (1%). | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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