Forgot your password?
New User?
Remember me
banner banner

You are here:Home » Antibodies » Antibodies-Antibiotics » Anti -Cyclosporin A (Antibiotic S 7481F1, Ciclosporin A, Ramihyphin A, CsA)

Anti -Cyclosporin A (Antibiotic S 7481F1, Ciclosporin A, Ramihyphin A, CsA)


  For pricing information, USA customers sign in.
  Outside USA? Please contact your distributor for pricing.


Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E
Cyclophilins are a highly conserved family of peptidylprolyl cis-trans-isomerases (PPIA) that are targets of the immunosuppressant drug cyclosporin A (CsA). The complex of cyclophilin and CsA can bind to and inhibit calcineurin which leads to inhibition of the transcription factor NFAT and decreased production of cytokines. As isomerases, cyclophilins have been proposed to aid in protein folding. Cyclophilin A can bind to the p55 Gag protein of HIV and appears necessary for HIV infection. There is also some evidence that cyclophilins can have nuclease activity and play a role in apoptosis.
Catalog #C8900-03
ApplicationsSuitable for use in ELISA. Other applications not tested.
Recommended DilutionsOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.  
Clone TypeMonoclonal
Clone No6D330
FormSupplied as a liquid in PBS, pH 7.4, 0.09% sodium azide.
PurityPurified by Protein G affinity chromatography.
ImmunogenCyclosporin A.
SpecificityRecognizes cyclosporin A in buffer solutions and whole blood extracts (KD=10-8).
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

External Links