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Cyclosporin A (Ciclosporin, Cyclorin, Neoral, Ramihyphin A, Sandimmun, Sandimmune, OL 27-400, S 7481F1, CyA, Antibiotic S 7481F1)
Cyclosporin A (Ciclosporin, Cyclorin, Neoral, Ramihyphin A, Sandimmun, Sandimmune, OL
27-400, S 7481F1, CyA, Antibiotic S 7481F1)
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| A fungal metabolite possessing potent immunosuppressive properties. It inhibits the T-cell receptor signal transduction pathway via the formation of cyclosporin A cyclophilin complex that inhibits calcineurin (protein phosphatase 2B). | | | Catalog # | C8900-05 | | Storage and Stability | Lyophilized powder may be stored at 4°C. Stable for 12 months at 4°C. Reconstitute with DMSO or ethanol. Aliquot to avoid repeated freezing and thawing. Store at 4°C. Reconstituted product is stable for 6 months at 4°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | 59865-13-3 | | Molecular Formula | C62H111N11O12 | | Molecular Weight | 1202.6 | | Source | Fusarium solani | | Purity | ~99% | | Form | Supplied as a white powder. | | Solubility | Ethanol, DMSO. Slightly soluble in water. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. | | Alternate names | Cyclosporine A |
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