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You are here:Home » Biochemicals » Biochem-Antibiotics » Cyclosporin A (Ciclosporin, Cyclorin, Neoral, Ramihyphin A, Sandimmun, Sandimmune, OL 27-400, S 7481F1, CyA, Antibiotic S 7481F1)

Cyclosporin A (Ciclosporin, Cyclorin, Neoral, Ramihyphin A, Sandimmun, Sandimmune, OL
27-400, S 7481F1, CyA, Antibiotic S 7481F1)

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Specifications

A fungal metabolite possessing potent immunosuppressive properties. It inhibits the T-cell receptor signal transduction pathway via the formation of cyclosporin A cyclophilin complex that inhibits calcineurin (protein phosphatase 2B).
Catalog #C8900-05
Storage and StabilityLyophilized powder may be stored at 4°C. Stable for 12 months at 4°C. Reconstitute with DMSO or ethanol. Aliquot to avoid repeated freezing and thawing. Store at 4°C. Reconstituted product is stable for 6 months at 4°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
CAS Number59865-13-3
Molecular FormulaC62H111N11O12
Molecular Weight1202.6
SourceFusarium solani
Purity~99%
FormSupplied as a white powder.
SolubilityEthanol, DMSO. Slightly soluble in water.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesCyclosporine A


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