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You are here:Home » Antibodies » Abs to Enzymes, Cytochrome » Anti -CYP17A1 (Steroid 17-alpha-hydroxylase/17,20 Lyase, CYPXVII, Cytochrome P450 17A1, Cytochrome P450-C17, Cytochrome P450c17, Steroid 17-alpha-monooxygenase, CYP17, S17AH)

Anti -CYP17A1 (Steroid 17-alpha-hydroxylase/17,20 Lyase, CYPXVII, Cytochrome P450 17A1,
Cytochrome P450-C17, Cytochrome P450c17, Steroid 17-alpha-monooxygenase, CYP17, S17AH)

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E B
Conversion of pregnenolone and progesterone to their 17-alpha-hydroxylated products and subsequently to dehydroepiandrosterone (DHEA) and androstenedione. Catalyzes both the 17-alpha-hydroxylation and the 17,20-lyase reaction. Involved in sexual development during fetal life and at puberty.
Catalog #C8929-03C1
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionELISA: 1:64,000
Western Blot: 0.1-0.3ug/ml, observed in human ovary lysates on ~60kD bands
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to C-LFKDGDQKLEK, from human CYP17A1, at the internal region of the protein (NP_000093.1).
SpecificityRecognizes human CYP17A1. Species sequence homology: Canine and feline.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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