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You are here:Home » Antibodies » Abs to Enzymes, Cytochrome » Anti -CYP24A1 (1,25-dihydroxyvitamin D(3) 24-hydroxylase, Mitochondrial, 24-OHase, Vitamin D(3) 24-hydroxylase, Cytochrome P450 24A1, Cytochrome P450-CC24, CYP24)

Anti -CYP24A1 (1,25-dihydroxyvitamin D(3) 24-hydroxylase, Mitochondrial, 24-OHase, Vitamin
D(3) 24-hydroxylase, Cytochrome P450 24A1, Cytochrome P450-CC24, CYP24)

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E B
CYP24A1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein initiates the degradation of 1,25-dihydroxyvitamin D3, the physiologically active form of vitamin D3, by hydroxylation of the side chain. In regulating the level of vitamin D3, this enzyme plays a role in calcium homeostasis and the vitamin D endocrine system.
Catalog #C8929-03F1
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionELISA: 1:32,000
Western Blot: 0.1-0.3ug/ml, human and rat liver lysates observed on ~50kD bands
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to C-RKYDIQATDN, from CYP24A1, at the internal region of the protein (NP_000773.2, NP_001122387.1).
SpecificityRecognizes CYP24A1. Species Crossreactivity: Human and rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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