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You are here:Home » Antibodies » Abs to Enzymes, Cytochrome » Anti -CYP7A1, CT (Cholesterol 7-alpha-hydroxylase, Cholesterol 7-alpha-monooxygenase, CYPVII, Cytochrome P450 7A1, CYP7)

Anti -CYP7A1, CT (Cholesterol 7-alpha-hydroxylase, Cholesterol 7-alpha-monooxygenase,
CYPVII, Cytochrome P450 7A1, CYP7)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Purified E B
CYP7A1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the first reaction in the cholesterol catabolic pathway in the liver, which converts cholesterol to bile acids. This reaction is the rate limiting step and the major site of regulation of bile acid synthesis, which is the primary mechanism for the removal of cholesterol from the body.
Catalog #C8929-05
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionELISA: 1:1,000
Western Blot: 1:50-1:100
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, 0.09% sodium azide.
PurityPurified by ammonium sulfate precipitation.
ImmunogenSynthetic peptide selected from the C-terminal region of human CYP7A1 (KLH).
SpecificityRecognizes human CYP7A1.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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