Cystatin A, Recombinant, Human, aa1-98, His-tag (Stefin A, Cystatin-A, Cystatin-AS,
Stefin-A, CSTA, STF1, STFA)
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| CSTA, also known as Stefin A, is thiol protease inhibitors that form complexes with papain and the cathepsins B, H and L. The protein is one of the precursor proteins of the cornified cell envelope in keratinocytes and plays a role in epidermal development and maintenance. CSTA is thought to be a tumor suppressor, since an inverse correlation seems to exist between the level of CSTA and tumor progression, in several malignancies. | | | Catalog # | C8949-18D | | Source | Recombinant corresponding to aa1-98 from human CSTA, fused to His-tag at N-terminus expressed in E.coli. | | AA Sequence | MGSSHHHHHH SSGLVPRGSH MIPGGLSEAK PATPEIQEIV DKVKPQLEEK TNETYGKLEA VQYKTQVVAG TNYYIKVRAG DNKYMHLKVF KSLPGQNEDL VLTGYQVDKN KDDELTGF | | Molecular Weight | ~13.1kD (118aa), confirmed by MALDI-TOF | | | | Storage and Stability: | | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | Molecular Weight | ~13.1kD | | Source | E.coli | | Purity | ~95% (SDS-PAGE) | | Concentration | ~1mg/ml | | Form | Supplied as a liquid in 20mM Tris-HCl buffer, pH 8, 1mM DTT, 10% glycerol. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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Download Specifications for Cystatin A, Recombinant, Human, aa1-98, His-tag (Stefin A, Cystatin-A, Cystatin-AS, Stefin-A, CSTA, STF1, STFA) |
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