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Anti -Cystatin A (Stefin A, Cystatin-A, Cystatin-AS, Stefin-A, CSTA, STF1, STFA)
Anti -Cystatin A (Stefin A, Cystatin-A, Cystatin-AS, Stefin-A, CSTA, STF1, STFA)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
IH |
|
| Stefin A is the intracellular inhibitor of cysteine proteinase cathepsin B (CatB) and belongs to family 1 of the cystatin superfamily of inhibitor proteins. It has been proposed that extracellular CatB together with other classes of proteinases are all subject to a cascade-like manner of activation. CatB and its inhibitor Stefin A are involved in degradation of extracellular matrix proteins during tissue remodeling. Stefin A had been reported to be in high concentrations in epithelial cells, polymorphonuclear leukocytes and lymphoid tissue. | | | Catalog # | C8949-18E | | Applications | Suitable for use in Immunohistochemistry. Other applications not tested. | | Recommended Dilution | Immunohistochemistry (Formalin fixed paraffin embedded): 1:200 for 10min at RT | | Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0 for 10min followed by cooling at RT for 20min. | | Optimal dilutions to be determined by the researcher. | | Positive Control | Appendix | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Host | Rabbit | | Source | Human | | Concentration | ~0.1mg/ml | | Form | Supplied as a liquid in PBS, pH 7.4, 0.2% BSA, 0.05% sodium azide. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Recombinant corresponding to full length human Stefin A. | | Specificity | Recognizes human Stefin A. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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