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You are here:Home » Antibodies » Abs to Protease Inhibitors » Anti -Cystatin C (AD8, Amyloid Angiopathy and Cerebral Hemorrhage, Cst3, Cystatin 3, Gamma Trace, HCCAA, Neuroendocrine Basic Polypeptide, Post gamma Globulin, ARMD11, MGC117328, OTTHUMP00000030440, OTTHUMP00000164181, bA218C14.4)

Anti -Cystatin C (AD8, Amyloid Angiopathy and Cerebral Hemorrhage, Cst3, Cystatin 3, Gamma
Trace, HCCAA, Neuroendocrine Basic Polypeptide, Post gamma Globulin, ARMD11, MGC117328,
OTTHUMP00000030440, OTTHUMP00000164181, bA218C14.4)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E
Cystatins are a superfamily of cysteine proteinase inhibitors found in both plants and animals. They comprise a group of proteinase inhibitors, widely distributed in tissues and body fluids, and form tight complexes with cysteine proteases such as cathepsin B, H, L and S. Cystatin C, a secreted molecule of this family, is of interest from biochemical, medical and evolutionary points of view. Cystatin C, with molecular weight of 13,260D, is composed of 146 amino acids, lacks carbohydrate and has two disulfide bridges located near the carboxyl terminus. Cystatin C is increased in patients with malignant diseases and is related to the insufficiency of renal function and appears to be a better marker than creatinine. On the other hand, low levels of cystatin C involve cause the breakdown of the elastic laminae and, subsequently, the atherosclerosis and abdominal aortic aneurysm.
Catalog #C8950-04
ApplicationsSuitable for use in ELISA. Other applications have not been tested.
Recommended Dilutions:
Optimal dilutions to be determined by the researcher.
Matched PairsCapture: C8950-04
Detection: C8950-09, C8950-06, C8950-10B
HybridomaSp2/0 myeloma I cells with spleen cells from Balb/c mice
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG1
Clone No8J181
HostMouse
SourceHuman
ConcentrationAs Reported
FormSupplied as a liquid in PBS, pH 7.4, 0.1% sodium azide
PurityPurified by Protein A afffinity chromatography. Purity is tested by electrophoresis(.>90% pure.)
ImmunogenCystatin C purified from human urine
SpecificityRecognizes human Cystatin C.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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