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You are here:Home » Antibodies » Abs to Protease Inhibitors » Anti -Cystatin C (AD8, Amyloid Angiopathy and Cerebral Hemorrhage, Cst3, Cystatin 3, Gamma Trace, HCCAA, Neuroendocrine Basic Polypeptide, Post gamma Globulin, ARMD11, MGC117328, OTTHUMP00000030440, OTTHUMP00000164181, bA218C14.4)

Anti -Cystatin C (AD8, Amyloid Angiopathy and Cerebral Hemorrhage, Cst3, Cystatin 3, Gamma
Trace, HCCAA, Neuroendocrine Basic Polypeptide, Post gamma Globulin, ARMD11, MGC117328,
OTTHUMP00000030440, OTTHUMP00000164181, bA218C14.4)

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E B
Cystatins are a superfamily of cysteine proteinase inhibitors found in both plants and animals. They comprise a group of proteinase inhibitors, widely distributed in tissues and body fluids, and form tight complexes with cysteine proteases such as cathepsin B, H, L and S. Cystatin C, a secreted molecule of this family, is of interest from biochemical, medical and evolutionary points of view. Cystatin C, with molecular weight of 13,260D, is composed of 146 amino acids, lacks carbohydrate and has two disulfide bridges located near the carboxyl terminus. Cystatin C is increased in patients with malignant diseases and is related to the insufficiency of renal function and appears to be a better marker than creatinine. On the other hand, low levels of cystatin C involve cause the breakdown of the elastic laminae and, subsequently, the atherosclerosis and abdominal aortic aneurysm.
Catalog #C8950-05F
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionPeptide ELISA: 1:8000
Western Blot: 0.01-0.03ug/ml. Band of ~18kD observed in mouse tesits and mouse kidney lysates.
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostGoat
SourceMouse
Concentration~0.5mg/ml
FormSupplied as a liquid in Tris saline, pH 7.3, 0.5% BSA, 0.02% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to GTHSLTKFSCKNA from the C terminus of mouse Cystatin C (NP_034106.2).
SpecificityRecognizes mouse Cystatin C.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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