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You are here:Home » Antibodies » Abs to Binding Proteins » Anti -Cysteine and Glycine-rich Protein 2 (CSRP2, Cysteine-rich Protein 2, CRP2, LIM Domain Only Protein 5, LMO-5, Smooth Muscle Cell LIM Protein, SmLIM, LMO5, SMLIM)

Anti -Cysteine and Glycine-rich Protein 2 (CSRP2, Cysteine-rich Protein 2, CRP2, LIM
Domain Only Protein 5, LMO-5, Smooth Muscle Cell LIM Protein, SmLIM, LMO5, SMLIM)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified B
CSRP2 (Cysteine-rich protein 2/CRP2; also Cysteine and Glycine-rich protein 2, LMO-5 and SmLIM) is a 21-22kD member of the CRP family of LIM domain-containing proteins. It is expressed in arterial smooth muscle, hepatic stellate cells and fibroblasts. CSRP2 is upregulated by TGF-b and downregulated by PDGF, and appears to interact with PIAS1 and CRP2-BP, thus promoting STAT signaling. It also binds to SRF and GATA4 to initiate smooth muscle differentiation. Human CSRP2 is 193aa in length and contains two 50aa LIM (for lin11/isl1/mec3) domains that contain two zinc-finger motifs (aa10-61 and 119-170), an NLS between aa64-69, and a Gly-rich C-terminus (aa176-187). Full-length human CSRP2 shares 79% aa identity with human CSRP1.
Catalog #C9001-10B
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionWestern Blot:2ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostGoat
SourceHuman
ConcentrationAs reported
FormSupplied as a lyophilized powder from a 0.2um filtered solution in PBS, 5% trehalose. Reconstitute in PBS, 0.02% sodium azide.
PurityPurified by Protein G affinity chromatography.
ImmunogenPurified, E. coli-derived full-length recombinant human CSRP2 (aa1-193; Accession #Q16527).
SpecificityRecognizes human CSRP2.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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