| CYR61 is a cysteine-rich, heparin-binding, growth factor belonging to the CCN family of secreted regulatory proteins. It stimulates chondrogensis and angiogenesis, playing an important role in cartilage and bone formation, as well as tumor growth and vascularization. |
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| Catalog # | C9018-01A |
| Applications | Suitable for use in Western Blot, Immunofluorescence, Immunocytochemistry and Immunohistochemistry. Other applications not tested. |
| Recommended Dilution | Immunohistochemistry (FFPE): 1:100 |
| Western Blot (ECL): 1:200. A band can be seen at ~37kD representing the processed form of CYR61 protein. |
| Optimal dilutions to be determined by the researcher. |
| Positive Control | MDA-MB-231 breast cancer cell lysate |
| Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. |
| CAS Number | n/a |
| Clone Type | Polyclonal |
| Isotype | IgG |
| Host | Rabbit |
| Source | Human |
| Concentration | ~1mg/ml |
| Form | Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide. |
| Purity | Purified by immunoaffinity chromatography. |
| Immunogen | Synthetic peptide corresponding to the human CYR61 protein sequence (between residues 150-250). |
| Specificity | Recognizes human CYR61. Species sequence homology: rat and mouse 88%. |
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| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
| Alternate names | CCN1, GIG1, IGFBP10, Cysteine-rich angiogenic induce 61, insulin-like growth factor-binding protein 10 |
