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You are here:Home » Antibodies » Abs to Transport Proteins » Anti -Cystinosin (CTNS, CTNS-LSB, PQLC4)

Anti -Cystinosin (CTNS, CTNS-LSB, PQLC4)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E IH
This gene encodes a seven-transmembrane domain protein that functions to transport cystine out of lysosomes. Its activity is driven by the H+ electrochemical gradient of the lysosomal membrane. Mutations in this gene cause cystinosis, a lysosomal storage disorder. Alternative splicing results in multiple transcript variants.
Catalog #C9070-50
ApplicationsSuitable for use in ELISA and Immunohistochemistry. Other applications not tested.
Recommended DilutionsELISA: 1:1-1:1000
Immunohistochemistry (Paraffin): 1.25ug/ml. Validated for use on a panel of 21 formalin-fixed, paraffin-embedded human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with C9070-50, slides were incubated with biotinylated Gt xRb IgG secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. 
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in PBS, 0.09% sodium azide.
PurityPurified by Protein G affinity chromatography.
ImmunogenSynthetic peptide corresponding to human Cystinosin conjugated to KLH.
SpecificityRecognizes aa268-285 of human Cystinosin.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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