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Anti -Cystinosin (CTNS, CTNS-LSB, PQLC4)
Anti -Cystinosin (CTNS, CTNS-LSB, PQLC4)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
E IH |
|
| This gene encodes a seven-transmembrane domain protein that functions to transport cystine out of lysosomes. Its activity is driven by the H+ electrochemical gradient of the lysosomal membrane. Mutations in this gene cause cystinosis, a lysosomal storage disorder. Alternative splicing results in multiple transcript variants. | | | Catalog # | C9070-50 | | Applications | Suitable for use in ELISA and Immunohistochemistry. Other applications not tested. | | Recommended Dilutions | ELISA: 1:1-1:1000 | | Immunohistochemistry (Paraffin): 1.25ug/ml. Validated for use on a panel of 21 formalin-fixed, paraffin-embedded human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with C9070-50, slides were incubated with biotinylated Gt xRb IgG secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | ~1mg/ml | | Form | Supplied as a liquid in PBS, 0.09% sodium azide. | | Purity | Purified by Protein G affinity chromatography. | | Immunogen | Synthetic peptide corresponding to human Cystinosin conjugated to KLH. | | Specificity | Recognizes aa268-285 of human Cystinosin. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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