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You are here:Home » Biochemicals » Biochem-Mycotoxins » Cytochalasin A

Cytochalasin A


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Cytochalasin A is one of a family of potent mycotoxins produced by several species of fungi. All members of the class exhibit profound effects on cytoskeletal proteins which give rise to pronounced morphogenic activity in animals and plants. Like most cytochalsins, cytochalasin A exhibits potent inhibition of actin filament function leading to cell death by apoptosis and displays a broad range of resultant cellular actions. Despite the common mode of action, there is evidence that individual members of this class display diverse selectivity. Specifically, cytochalasin A was shown to be one of the few cytochalasins exhibiting activity against HIV-1 protease.
Catalog #C9093-51
SourceCytochalasin A from Drechslera dematoidea.
Molecular Weight~477.6
SolubilitySoluble in ethanol, methanol, DMF or DMSO.
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with DMSO. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
CAS Number14110-64-6
Molecular FormulaC29H35NO5
Molecular Weight~477.6
Purity~98% (HPLC)
ConcentrationNot determined
FormSupplied as a white powder.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. Toxicity and Hazards: All products should be handled by qualified personnel only, trained in laboratory procedures.

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