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You are here:Home » Biochemicals » Biochem-Mycotoxins » Cytochalasin B

Cytochalasin B


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Cytochalasin B is one of the most extensively studied members of a family of potent mycotoxins produced by several species of fungi. All members of the class exhibit profound effects on cytoskeletal proteins which give rise to pronounced morphogenic activity in animals and plants. Like most cytochalsins, cytochalasin B exhibits potent inhibition of actin filament function leading to cell death by apoptosis and displays a broad range of resultant cellular actions. Despite the common mode of action, class there is evidence that individual members of this class display diverse selectivity. However, lack of comparative co-metabolite analysis has restricted a more complete understanding of their individual selectivity.
Catalog #C9093-52
Molecular Weight479.6
SolubilitySoluble in ethanol, methanol, DMF or DMSO. Poor water solubility.
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile buffer. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
CAS Number14930-96-2
Molecular FormulaC29H37NO5
Molecular Weight479.6
SourceDrechslera dematoidea
Purity~99% (HPLC)
ConcentrationNot Determined
FormSupplied as a white powder
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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