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Anti -Cytochrome C (CYC, Cytochrome C Somatic, CYCS, HCS, THC4) (Biotin)
Anti -Cytochrome C (CYC, Cytochrome C Somatic, CYCS, HCS, THC4) (Biotin)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Affinity Purified |
B |
|
| In addition to its well-known role in electron transport, cytochrome c (CYT) has been identified as a mediator of apoptosis or programmed cell death. Cytochrome c translocates from mitochondria into the cytoplasm in the early phases of apoptosis and plays a role in initiation of the apoptotic proteolytic cascade by activating caspase-3. Cytochrome c has been shown to bind Apaf-1. Apaf-1 has also been shown to activate capase-3. | | | Catalog # | C9095-02C | | Applications | Suitable for use in Western Blot. Other applications not tested. | | Recommended Dilution | Western Blot: 1:250-1:500 | | Optimal dilutions to be determined by the researcher. | | Positive Control | HeLa cells lysate | | Storage and Stability | Store at 4°C. Do Not Freeze. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG2b | | Clone No | 7H8.2C12 | | Host | Mouse | | Source | Pigeon | | Concentration | ~0.25mg/ml | | Form | Supplied as a liquid in PBS. No preservative and no stabilizing protein added. Labeled with Biotin. | | Purity | Purified by Protein G affinity chromatography. | | Immunogen | Synthetic peptides corresponding to aa1-80, 81-104 and 66-104 of pigeon CYT. Epitope: Within aa93-104 of pigeon CYT. | | Specificity | Recognizes pigeon CYT (~15kD). Species Crossreactivity: Human, mouse, rat, hamster, equine and Drosophila. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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