Login

Forgot your password?
New User?
Remember me
banner banner

You are here:Home » Antibodies » Abs to Enzymes, Cytochrome » Anti -Cytochrome C (CYC, Cytochrome C Somatic, CYCS, HCS, THC4) (Biotin)

Anti -Cytochrome C (CYC, Cytochrome C Somatic, CYCS, HCS, THC4) (Biotin)

Pricing

  For pricing information, USA customers sign in.
  Outside USA? Please contact your distributor for pricing.

Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified B
In addition to its well-known role in electron transport, cytochrome c (CYT) has been identified as a mediator of apoptosis or programmed cell death. Cytochrome c translocates from mitochondria into the cytoplasm in the early phases of apoptosis and plays a role in initiation of the apoptotic proteolytic cascade by activating caspase-3. Cytochrome c has been shown to bind Apaf-1. Apaf-1 has also been shown to activate capase-3.
Catalog #C9095-02C
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 1:250-1:500
Optimal dilutions to be determined by the researcher.
Positive ControlHeLa cells lysate
Storage and StabilityStore at 4°C. Do Not Freeze. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG2b
Clone No7H8.2C12
HostMouse
SourcePigeon
Concentration~0.25mg/ml
FormSupplied as a liquid in PBS. No preservative and no stabilizing protein added. Labeled with Biotin.
PurityPurified by Protein G affinity chromatography.
ImmunogenSynthetic peptides corresponding to aa1-80, 81-104 and 66-104 of pigeon CYT. Epitope: Within aa93-104 of pigeon CYT.
SpecificityRecognizes pigeon CYT (~15kD). Species Crossreactivity: Human, mouse, rat, hamster, equine and Drosophila.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


External Links