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You are here:Home » Antibodies » Abs to Enzymes, Cytochrome » Anti -Cytochrome P450 1A1

Anti -Cytochrome P450 1A1

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Purified E B
Phase 1 drug metabolism is catalyzed by two groups of monooxygenases, the cytochrome P450s (CYPs) and the flavin monooxygenases (FMOs). Both CYPs and FMOs are localized in the endoplasmic reticulum. Collectively, these enzymes catalyze the oxidation of a very broad range of substrates. Both classes are dependent on NADPH as a source of electrons, but the two classes exhibit significant differences in mechanism and substrate specificity.
Catalog #C9095-11D
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 1:1000
Optimum dilutions to be determined by researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG
Clone No4i180
HostMouse
SourceRat
Concentration~0.5mg/ml
FormSupplied as a liquid in PBS containing 0.1% gelatin and 0.05% sodium azide.
PurityPurified by caprylic acid and ammonium sulfate precipitation.
ImmunogenRecombinant rat Cytochrome P450 (1A1)
SpecificityRecognizes rat Cytochrome P450 1A1 (~58kD). Does not crossreact with 1A2.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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