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Specifications

Clone Host Grade Applications Monoclonal Mouse Purified E B

Phase 1 drug metabolism is catalyzed by two groups of monooxygenases, the cytochrome P450s (CYPs) and the flavin monooxygenases (FMOs). Both CYPs and FMOs are localized in the endoplasmic reticulum. Collectively, these enzymes catalyze the oxidation of a very broad range of substrates. Both classes are dependent on NADPH as a source of electrons, but the two classes exhibit significant differences in mechanism and substrate specificity.
Catalog #	C9095-11D
Applications	Suitable for use in ELISA and Western Blot. Other applications not tested.
Recommended Dilution	Western Blot: 1:1000
	Optimum dilutions to be determined by researcher.
Storage and Stability	May be stored at 4°C for short-term only. For long-term storage, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
CAS Number	n/a
Clone Type	Monoclonal
Isotype	IgG
Clone No	4i180
Host	Mouse
Source	Rat
Concentration	~0.5mg/ml
Form	Supplied as a liquid in PBS containing 0.1% gelatin and 0.05% sodium azide.
Purity	Purified by caprylic acid and ammonium sulfate precipitation.
Immunogen	Recombinant rat Cytochrome P450 (1A1)
Specificity	Recognizes rat Cytochrome P450 1A1 (~58kD). Does not crossreact with 1A2.
Important Note	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.