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You are here:Home » Molecular Biology » MB-Cloning-cDNA » Cytochrome P450 1A1, cDNA Probe, Human, BioGenomics™

Cytochrome P450 1A1, cDNA Probe, Human, BioGenomics™


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Phase 1 drug metabolism is catalyzed by two groups of monooxygenases, the cytochrome P450s (CYPs) and the flavin monooxygenases (FMOs). Both CYPs and FMOs are localized in the endoplasmic reticulum. Collectively, these enzymes catalyze the oxidation of a very broad range of substrates. Both classes are dependent on NADPH as a source of electrons, but the two classes exhibit significant differences in mechanism and substrate specificity.
Catalog #C9095-11K
Size of the cDNA3.6Kb
ApplicationsSuitable for use for the synthesis, by standard random priming or nick translation techniques, of radiolabeled probes for investigations of P450 1A1 gene expression. Other applications not tested.
Optimum dilutions to be determined by researcher.
Storage and StabilityCan be stored for at least one year at -70°C. Avoid repeated freeze/thaw cycles.
FormSupplied in TE buffer.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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