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Specifications

Clone Host Grade Applications Polyclonal Rabbit Serum B N

Catalog #	C9095-12A
P450 enzymes are divided into two groups	steroidogenic and xenobiotic. The latter group is comprised of three families 1, 2 and 3. The xenobiotic p450's are involved in most oxidative drug metabolism. Work in this area is ongoing but studies suggest that all known drug metabolism is mediated by family members:CYP3A, CYP2D6, CYP1A2, CYP2C9/10, CYP2C19 and CYP2E1.
Applications	Suitable for use in Western Blot and Functional Assays. Other applications not tested.
Recommended Dilution	Western Blot: 1:5000-1:10,000
	Inhibition Assays: 1-20ul
	Optimal working dilutions to be determined by researcher.
Storage and Stability	May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add 40-50% glycerol, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
CAS Number	n/a
Clone Type	Polyclonal
Isotype	IgG
Host	Rabbit
Source	Human
Concentration	Not determined
Form	Supplied as a liquid.
Purity	Serum.
Immunogen	Purified human CYP1A2 expressed in E.Coli.
Specificity	Recognizes human cytochrome p450 1A2 (CYP1A2). The product is a neutralizing antibody which is a specific and potent inhibitor of CYP1A2 activity.
Important Note	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.