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You are here:Home » Antibodies » Abs to Enzymes, Cytochrome » Anti -Cytochrome p450 1A2 (CYP1A2)

Anti -Cytochrome p450 1A2 (CYP1A2)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Serum B N
Catalog #C9095-12A
P450 enzymes are divided into two groups steroidogenic and xenobiotic. The latter group is comprised of three families 1, 2 and 3. The xenobiotic p450's are involved in most oxidative drug metabolism. Work in this area is ongoing but studies suggest that all known drug metabolism is mediated by family members:CYP3A, CYP2D6, CYP1A2, CYP2C9/10, CYP2C19 and CYP2E1.
ApplicationsSuitable for use in Western Blot and Functional Assays. Other applications not tested.
Recommended DilutionWestern Blot: 1:5000-1:10,000
Inhibition Assays: 1-20ul
Optimal working dilutions to be determined by researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add 40-50% glycerol, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationNot determined
FormSupplied as a liquid.
PuritySerum.
ImmunogenPurified human CYP1A2 expressed in E.Coli.
SpecificityRecognizes human cytochrome p450 1A2 (CYP1A2). The product is a neutralizing antibody which is a specific and potent inhibitor of CYP1A2 activity.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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