| Aromatase is a key enzyme in steroidogenesis and plays an important role in sexual differentiation, fertility, and carcinogenesis. Many environmental chemicals may influence aromatase activity and thereby disrupt endocrine function. |
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| Catalog # | C9095-14B |
| Cellular Localization | Membrane-bound |
| Applications | Suitable for use in ELISA and Western Blot. Other applications not tested. |
| Recommended Dilution | Western Blot: 1ug/ml (ECL). A band is seen at ~55kD. |
| Optimal dilutions to be determined by the researcher. |
| Storage and Stability | May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%) Freeze at -20°C or colder. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. |
| CAS Number | n/a |
| Clone Type | Polyclonal |
| Host | Rabbit |
| Source | Human |
| Concentration | ~1mg/ml |
| Form | Supplied as a liquid in Tris-citrate/phosphate, pH 7-8. |
| Purity | Purified by immunoaffinity chromatography. |
| Immunogen | A synthetic peptide made to a C-terminal portion of the human aromatase protein sequence (between residues 400-502). Homology: 100% Mk, 91% Eq, 90% Bv, Rb, 83% Po, 81% Sh, Gt, and Ca |
| Specificity | This antibody is specific for aromatase. Species Crossreactivity: This antibody reacts with human aromatase protein. The immunogen used for this antibody production has 100% homology with monkey, 91% with horse, 90% with bovine and rabbit, 83% with porcine, and 81% with sheep, goat, and canine. There is no significant homology with rat or mouse protein. |
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| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
| Alternate names | ARO1, CYAR, CYP19, CYP19A1, CYPXIX, Cytochrome P450 19A1, Estrogen synthetase, P-450AROM |
