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You are here:Home » Antibodies » Abs to Enzymes, Cytochrome » Anti -Cytochrome p450 2C19 (CYP2C19)

Anti -Cytochrome p450 2C19 (CYP2C19)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Serum
P450 enzymes are divided into two groups: steroidogenic and xenobiotic. The latter group is comprised of three families 1, 2 and 3. The xenobiotic p450's are involved in most oxidative drug metabolism. Work in this area is ongoing but studies suggest that all known drug metabolism is mediated by family members:CYP3A, CYP2D6, CYP1A2, CYP2C9/10, CYP2C19 and CYP2E1. The CYP2C19 p450 is reported to be genetically polymorphic which gives rise to populations which are genetically deficient in CYP2C19. AHP628Z is a neutralizing antibody which is a specific and potent inhibitor of CYP2C19.
Catalog #C9095-15D
ApplicationsSuitable for use in Functional Assays. Not suitable for use in Western Blot. Other applications not tested.
Recommended DilutionsFunctional Assays: 2-20ul.
Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationNot determined
FormSupplied as a liquid. No preservatives added.
PuritySerum.
ImmunogenPurified human CYP2C19 expressed in E. coli.
SpecificityRecognizes human cytochrome p450 2C19 (CYP2C19).
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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