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You are here:Home » Antibodies » Abs to Enzymes, Cytochrome » Anti -CYP2C8, NT (S-mephenytoin 4-hydroxylase, Cytochrome P450 IIC2, P450 Cytochrome MP-12/MP-20, Cytochrome P450 Form 1, CYPIIC8, Cytochrome P450 2C8)

Anti -CYP2C8, NT (S-mephenytoin 4-hydroxylase, Cytochrome P450 IIC2, P450 Cytochrome
MP-12/MP-20, Cytochrome P450 Form 1, CYPIIC8, Cytochrome P450 2C8)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Purified E B
CYP2C8 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to metabolize many xenobiotics, including the anticonvulsive drug mephenytoin, benzo(a)pyrene, 7-ethyoxycoumarin, and the anti-cancer drug taxol.
Catalog #C9095-15F1
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionELISA: 1:1,000
Western Blot: 1:50-1:100
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, 0.09% sodium azide.
PurityPurified by ammonium sulfate precipitation.
ImmunogenSynthetic peptide selected from the N-terminal region of human CYP2C8 (KLH).
SpecificityRecognizes human CYP2C8.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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